Being about 2" off the ground will help a lot. Coil-overs front and or rear with and IRS in the back out of a 'vet, which supposedly is just a bolt on...according so somebody who has done it. Not sure on that though. Thick sway bars front and rear will help, stiff shocks as well.
And that should give you some great handling but remember to handle good, you loose the ride, but S10 don't start out toooo good in that area anyways.
Well I guess it depends on how good you are at metal work..lol This guy showed me pics and said there wasn't much work to it for an S10, I was like OK, but hell it'd be a task for me to do it. Easy for him I guess..lol