With the heads and piston combo your running I'd figure you've got around 8/8.5 to 1 compression.Longer duration will kill the bottom end like you said it did.
Try calling comp cams their Extreme series has openings and closings that are supposed to help cylinder pressure.
I had the same problem years ago w/a comp magnum 292 cam,in a stock bottom end 350.Sounds like your following the same path I went down.
BTW,when I changed from a mld roller to a much bigger one I went from,220 cranking pressure to 190,and picked up over 1/2 a second.
Try calling comp cams their Extreme series has openings and closings that are supposed to help cylinder pressure.
I had the same problem years ago w/a comp magnum 292 cam,in a stock bottom end 350.Sounds like your following the same path I went down.
BTW,when I changed from a mld roller to a much bigger one I went from,220 cranking pressure to 190,and picked up over 1/2 a second.